Linking advances in our understanding to sustainable production of pig meat requires a more lateral perspective centred on the primary drivers of sustainability. This chapter considers advances in nutritional requirements and metabolism and how these contribute to sustainable production of pig meat, including the need to maintain sow body condition throughout gestation and lactation and ways of reducing variation in pork production systems. The chapter examines strategic use of metabolic modifiers and the importance of matching nutrient requirements to pig diet specifications and optimising gut health and nutrient utilisation capacity. The chapter provides a useful overview of understanding the interaction between nutrition and pig health.