The Anthology of the Works of Ugo Spirito captures the trajectory of Ugo Spirito’s complex body of thought that spanned more than fifty years, from 1921 to 1977. While confronting difficult contemporary problems related to philosophy and science, liberalism and socialism, fascism and communism, and other economic and ideological aspects such as corporativism and democracy, Spirito revealed a persistent desire to reach truth and the absolute. Yet, he also voiced his failure to remain faithful to any philosophical or political system considered definitive and unquestionable. Unable to reach incontrovertibility, he consistently dissected the prevailing contemporary ideas and systems, including his own beliefs, developing at the same time the ‘antinomic’ approach, a method of critical analysis that undermined any truth reputed irrefutable. Today, Spirito stands as one of most anti-conformist Italian thinkers for he challenged the certainties of modern thought.