Recounts the various styles of leadership shown by several prominent German chemists and biochemists during the period 1830 to 1914. Featured particularly are chemists Liebig, Baeyer and Emil Fischer and biochemists Hoppe-Seyler, Kuhne and Hofmeister. In a final chapter, Fruton considers the relevance of the conclusions drawn from the style of these 19th- and early 20th-centuy men to the styles of more recent research groups in the chemical and biochemical sciences. Special emphasis is placed on their influence on their scientific progenies in Germany, and in England, Russia, and the U.S. Attention is given to the individual contributions of the junior members of these scientific groups to the growth of knowledge within their disciplines.