This tenth volume of papers emanating from the annual International High Technology Small Firms Conference represents a full decade of research and policy relevant papers on innovation and growth problems of New Technology-based Firms (NTBf). Because this series has become the major vehicle for publication among the best international researchers working on the formation and subsequent growth problems of NTBfs, it represents an authoritative voice on NTBf development problems. Topics covered in this volume include strategy, spin offs - their contribution to NTBf growth and the problems they encounter during the traumatic spin off process, the current hot topic of clusters and their role in enhancing NTBf formation and growth, networking and global issues since many NTBfs are truly born global.