This book is intended primarily for people who want to learn both Python 3 and how to use ChatGPT with Python. Chapter One begins with an introduction to fundamental aspects of Python programming, including various data types, number formatting, Unicode and UTF-8 handling, and text manipulation techniques. Later, the book covers loops, conditional logic, and reserved words in Python. You will also see how to handle user input, manage exceptions, and work with command-line arguments. Next, the text transitions to the realm of Generative AI, discussing its distinction from Conversational AI. Popular platforms and models, including ChatGPT, GPT-4, and their competitors, are presented to give readers an understanding of the current AI landscape. The book also sheds light on the capabilities of ChatGPT, its strengths, weaknesses, and potential applications. In addition, you will learn how to generate a variety of Python 3 code samples via ChatGPT using the “Code Interpreter” plugin. Code samples and figures from the book are available for downloading. In essence, the book provides a modest bridge between the worlds of Python programming and AI, aiming to equip readers with the knowledge and skills to navigate both domains confidently.