The great majority of modern agro-ecosystems comprise rotations of a small number of crop species where each year’s crop is a genetically uniform monoculture. The narrow genetic basis for disease resistance in modern cultivars increases the potential for pathogens to overcome this resistance and attack a large number of plants at a similar state of development. In this chapter, we present a number of strategies for limiting foliar disease development in wheat and barley. We discuss how crop rotations with non-cereal species can substantially reduce inoculum sources for residue-borne cereal leaf diseases. Further strategies, such as intercropping, gene deployment and conversation tillage, are then presented, with discussion of the effectiveness of each strategy against particular foliar diseases. It is concluded that there is potential for residue-borne cereal leaf diseases to be managed under conservation tillage via crop rotation, fungicide application and careful choice of variety.