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The Understanding, Prevention and Control of Human Cancer is an account of how a married couple opened understanding of environmental carcinogenesis. Elizabeth Cavert and James A. Miller showed that enzymes of the human body activate and enable otherwise benign organic chemicals to combine with DNA in such a manner that cancer results. Their work is of particular note because cancer causes more loss of life-years than the sum of all other causes of death—and, as the President’s (USA) Cancer Panel warned, environmental carcinogenesis is a form of cancer that has been previously “grossly underestimated”. The Millers’ cancer research led to tests that identify dangerous chemicals which in turn permits prevention and thus the control of human cancer.
Price: $61.00
Pages: 196
Publisher: Brill
Imprint: Brill
Series: History of Science and Medicine Library
Publication Date:
06 November 2015
ISBN: 9789004286795
Format: Hardcover
"A seminal paper authored in 1947 by Elizabeth C. Miller (1920–87) and James A. Miller (1915–2000) provided the first clue to an underlying common mechanism for the biological activities of chemical carcinogens. […] Robert G. McKinnell has recently published an excellent biography of James and Elizabeth Miller, motivated in part by his desire ‘that the Millers should be recognized by the myriads of ordinary people whose lives have been impacted for the better.’" - Norman Drinkwater, University of Wisconsin-Madison, in: Medical History 61.1 (January 2017)
Robert G. McKinnell, Ph.D. (1959), is a Morse/Alumni Professor Emeritus at the University of Minnesota. He has published scientific studies on animal cloning and herpesvirus cancer. He was a Royal Society of London Guest Research Fellow at the University of Oxford and he was awarded the Prince Hitachi Prize for basic cancer research by the Japanese Cancer Institute, Tokyo.