The cost of animal production is mainly dependent on the feeding price, almost 70% of the total production cost per animal. These animals need specific nutritional requirements, and it can be typically met through conventional feed ingredients like soybean meals, corn, and wheat. However, rising prices and limited availability of these traditional feed ingredients, along with growing environmental concerns, have created pressure on global feed systems and highlighted the need for alternative protein sources. Rapeseed meals have become the second most widely produced protein ingredient although the inclusion of/RSM in animal diets presents opportunities for reducing dependency on traditional feed ingredients, addressing concerns related to food security and promoting sustainable agricultural practices on successful incorporation of these ingredients particularly in monogastric diets requires careful consideration. Therefore, in this chapter, we aim to address the advantages and disadvantages of using canola/ rapeseed co-products as novel in-feed ingredients in monogastric animals’ nutrition.