Post-harvest deterioration in the quality of mangoes is determined in large measure by pre-harvest factors ranging from the cultivar grown to orchard management and harvest practices. This chapter describes the changes related to ripening in mangoes and the pre-harvest, in-harvest and post-harvest practices which can lead to deterioration or damage. The chapter also addresses measures that can be taken to modify mangoes to reduce the risk of deterioration and damage, including fruit thinning and individual fruit bagging or nets. The chapter discusses viable and cost-effective solutions to mango damage and deterioration and looks ahead to future trends in this area.