Cassava is an important staple crop for the food security of millions of people in developing countries. This chapter examines the strengths and weaknesses of cassava roots and leaves as a source of nutrients, and describes and analyses efforts to promote biofortified varieties of cassava with higher carotenoid levels that could help tackle vitamin A deficiency. The chapter describes in detail the range of products that can be processed from cassava roots and leaves and assesses their nutritional value, as well as analyses the chemical composition of roots and leaves. The chapter includes a case study on the use of biofortified cassava to make two traditional products, gari and fufu, in Nigeria, and suggests future directions that research may take in this area.